4JE4
Crystal Structure of Monobody NSa1/SHP2 N-SH2 Domain Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 11 | polymer | 106 | 12104.6 | 1 | UniProt (Q06124) Pfam (PF00017) | Homo sapiens (human) | Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3 |
| 2 | B (B) | Monobody NSa1 | polymer | 94 | 10129.2 | 1 | Pfam (PF00041) UniProt (by SIFTS) (P02751) | Homo sapiens (human) | |
| 3 | C, D (A, B) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A: 1 - 103 (UniProt: Q06124)
| PDB | External Database | Details |
|---|---|---|
| Lys 104 | - | expression tag |
| Glu 105 | - | expression tag |
| Lys 106 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22233.8 | |
| All* | Total formula weight | 22233.8 |
