4JD6

Crystal structure of Mycobacterium tuberculosis Eis in complex with coenzyme A and tobramycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Enhanced intracellular survival protein	polymer	428	46660.8	6	UniProt (I6X469) Pfam (PF13527) Pfam (PF17668) Pfam (PF13530) UniProt (by SIFTS) (P9WFK7)	Mycobacterium tuberculosis
2	G, I, K, L, M... (A, B, C, D, E...)	COENZYME A	non-polymer		767.5	6	Chemie (COA)
3	H, J (A, B)	TOBRAMYCIN	non-polymer		467.5	2	Chemie (TOY)

Sequence modifications

A, B, C, D, E, F: 1 - 402 (UniProt: I6X469)

PDB	External Database	Details
Met -25	-	expression tag
Gly -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Leu -12	-	expression tag
Val -11	-	expression tag
Pro -10	-	expression tag
Arg -9	-	expression tag
Gly -8	-	expression tag
Ser -7	-	expression tag
His -6	-	expression tag
Met -5	-	expression tag
Leu -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asp -1	-	expression tag
Ser 0	-	expression tag
Ala 204	Cys 204	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	279965.0
Non-Polymers*	Number of molecules	8
	Total formula weight	5540.2
All*	Total formula weight	285505.3

*Water molecules are not included.