4J9D
Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | Tyrosine-protein kinase ABL1 | polymer | 63 | 6966.7 | 3 | UniProt (P00519) Pfam (PF00018) In PDB | Homo sapiens (human) | Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150 |
| 2 | B, D, F | P0 | polymer | 11 | 1075.3 | 3 | UniProt (by SIFTS) (Q9Y3L3) In PDB | ||
| 3 | E | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A, C, E: 60 - 121 (UniProt: P00519)
| PDB | External Database | Details |
|---|---|---|
| Met 59 | - | initiating methionine |
| Ala 114 | Asn 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 24125.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 24221.8 |
