4J9D
Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P0
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 201 |
| Chain | Residue |
| E | GLU86 |
| E | LYS87 |
| E | LYS105 |
| E | HOH311 |
| E | HOH342 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR CHAIN B OF P0 |
| Chain | Residue |
| A | LYS84 |
| A | ASN94 |
| A | GLU98 |
| A | TRP99 |
| A | LYS105 |
| A | ASN106 |
| A | TRP110 |
| A | TYR115 |
| A | HOH210 |
| A | HOH237 |
| A | HOH238 |
| B | HOH101 |
| B | HOH102 |
| B | HOH103 |
| B | HOH104 |
| B | HOH106 |
| B | HOH107 |
| B | HOH108 |
| C | ASN96 |
| A | TYR70 |
| A | TYR70 |
| A | SER75 |
| A | ASP77 |
| site_id | AC3 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR CHAIN D OF P0 |
| Chain | Residue |
| C | TYR70 |
| C | SER75 |
| C | ASP77 |
| C | ASN78 |
| C | THR79 |
| C | ASN94 |
| C | GLU98 |
| C | TRP99 |
| C | LYS105 |
| C | ASN106 |
| C | TRP110 |
| C | TYR115 |
| C | HOH224 |
| D | HOH101 |
| D | HOH102 |
| D | HOH104 |
| D | HOH105 |
| D | HOH107 |
| D | HOH110 |
| D | HOH111 |
| D | HOH112 |
| E | TYR70 |
| E | LYS84 |
| E | HOH303 |
| E | HOH360 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR CHAIN F OF P0 |
| Chain | Residue |
| C | TYR70 |
| C | LYS84 |
| C | HOH208 |
| C | HOH247 |
| E | TYR70 |
| E | SER75 |
| E | ASP77 |
| E | ASN94 |
| E | GLU98 |
| E | TRP99 |
| E | LYS105 |
| E | ASN106 |
| E | TRP110 |
| E | PRO112 |
| E | TYR115 |
| E | HOH321 |
| E | HOH335 |
| F | HOH101 |
| F | HOH102 |
| F | HOH103 |
| F | HOH104 |
| F | HOH105 |
| F | HOH107 |
| F | HOH109 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"16912036","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18775435","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"16912036","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
