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4J8S

Crystal structure of human CNOT1 MIF4G domain in complex with a TTP peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CCR4-NOT transcription complex subunit 1polymer20324033.31UniProt (A5YKK6)
Pfam (PF16417)
Homo sapiens (human)CCR4-associated factor 1, Negative regulator of transcription subunit 1 homolog, NOT1H, hNOT1
2B
(B)
Tristetraprolinpolymer151758.11UniProt (P26651)HOMO SAPIENSTTP, G0/G1 switch regulatory protein 24, Growth factor-inducible nuclear protein NUP475, Protein TIS11A, TIS11, Zinc finger protein 36 homolog, Zfp-36
3C, D
(A, B)
waterwater18.0237Chemie (HOH)
Sequence modifications
A: 795 - 994 (UniProt: A5YKK6)
PDBExternal DatabaseDetails
Ser 792-expression tag
Gly 793-expression tag
Phe 794-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight25791.3
All*Total formula weight25791.3
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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