4J8F

Crystal structure of a fusion protein containing the NBD of Hsp70 and the middle domain of Hip

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Heat shock 70 kDa protein 1A/1B, Hsc70-interacting protein	polymer	561	62418.5	1	UniProt (P08107) UniProt (P50503) Pfam (PF00012) UniProt (by SIFTS) (P0DMV8) In PDB	Homo sapiens (human brown rat rat rats)
2	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
3	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	A	IODIDE ION	non-polymer		126.9	17	Chemie (IOD)
6		water	water		18.0	45	Chemie (HOH)

Sequence modifications

A: 1 - 382 (UniProt: P08107)

PDB	External Database	Details
Gly -6	-	expression tag
Ala -5	-	expression tag
Met -4	-	expression tag
Asp -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

A: 384 - 554 (UniProt: P50503)

PDB	External Database	Details
Leu 383	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	62418.5
Non-Polymers*	Number of molecules	20
	Total formula weight	2703.8
All*	Total formula weight	65122.3

*Water molecules are not included.