4J7F

SET7/9Y335pAF in complex with TAF10 peptide and AdoHcy

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Histone-lysine N-methyltransferase SETD7	polymer	261	29042.3	1	UniProt (Q8WTS6) Pfam (PF22648) Pfam (PF00856)	Homo sapiens (human)	Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET7/9
2	B (B)	Transcription initiation factor TFIID subunit 10	polymer	11	1255.5	1	UniProt (Q12962)	Homo sapiens	STAF28, Transcription initiation factor TFIID 30 kDa subunit, TAF(II)30, TAFII-30, TAFII30
3	C (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
4	D, E (A, B)	water	water		18.0	171	Chemie (HOH)

Sequence modifications

A: 110 - 366 (UniProt: Q8WTS6)

PDB	External Database	Details
Gly 106	-	expression tag
Ala 107	-	expression tag
Met 108	-	expression tag
Gly 109	-	expression tag
Hox 335	Tyr 335	engineered mutation

B: 186 - 195 (UniProt: Q12962)

PDB	External Database	Details
Ace 185	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30297.8
Non-Polymers*	Number of molecules	1
	Total formula weight	384.4
All*	Total formula weight	30682.2

*Water molecules are not included.