4J6G
CRYSTAL STRUCTURE OF LIGHT AND DcR3 COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tumor necrosis factor ligand superfamily member 14 | polymer | 165 | 18188.5 | 2 | UniProt (O43557) Pfam (PF00229) | Homo sapiens (human) | Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand, Tumor necrosis factor ligand superfamily member 14, membrane form, Tumor necrosis factor ligand superfamily member 14, soluble form |
| 2 | C, D (C, D) | Tumor necrosis factor receptor superfamily member 6B | polymer | 174 | 19044.2 | 2 | UniProt (O95407) Pfam (PF00020) | Homo sapiens (human) | Decoy receptor 3, DcR3, Decoy receptor for Fas ligand, M68 |
| 3 | E (E) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 4 | F, G (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | H, J (C, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | I (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, B: 83 - 240 (UniProt: O43557)
C, D: 30 - 195 (UniProt: O95407)
| PDB | External Database | Details |
|---|---|---|
| His 76 | - | expression tag |
| His 77 | - | expression tag |
| His 78 | - | expression tag |
| His 79 | - | expression tag |
| His 80 | - | expression tag |
| His 81 | - | expression tag |
| Gly 82 | - | expression tag |
| Glu 214 | Lys 214 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Thr 196 | - | expression tag |
| Gly 197 | - | expression tag |
| His 198 | - | expression tag |
| His 199 | - | expression tag |
| His 200 | - | expression tag |
| His 201 | - | expression tag |
| His 202 | - | expression tag |
| His 203 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 74465.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 340.7 | |
| All* | Total formula weight | 75554.9 |
