4J4Q
Crystal structure of active conformation of GPCR opsin stabilized by octylglucoside
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Rhodopsin | polymer | 348 | 39031.5 | 1 | UniProt (P02699) Pfam (PF10413) Pfam (PF00001) In PDB | Bos taurus (bovine) | |
2 | B | Guanine nucleotide-binding protein G(t) subunit alpha-1 | polymer | 11 | 1261.5 | 1 | UniProt (P04695) In PDB | Bos taurus | Transducin alpha-1 chain |
3 | C | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
4 | D | alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900006) GlyTouCan (G92130SN) | trehalose | ||
5 | A | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 4 | Chemie (BOG) | |||
6 | A | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
7 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
8 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
9 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
B: 340 - 350 (UniProt: P04695)
PDB | External Database | Details |
---|---|---|
Leu 341 | Lys 341 | engineered mutation |
Val 347 | Cys 347 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 40292.9 | |
Branched | Number of molecules | 2 |
Total formula weight | 1091.0 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1677.1 | |
All* | Total formula weight | 43061.0 |