4J4Q
Crystal structure of active conformation of GPCR opsin stabilized by octylglucoside
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rhodopsin | polymer | 348 | 39031.5 | 1 | UniProt (P02699) Pfam (PF10413) Pfam (PF00001) | Bos taurus (bovine) | |
| 2 | B (B) | Guanine nucleotide-binding protein G(t) subunit alpha-1 | polymer | 11 | 1261.5 | 1 | UniProt (P04695) | Bos taurus | Transducin alpha-1 chain |
| 3 | C (C) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 4 | D (D) | alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900006) GlyTouCan (G92130SN) | trehalose | ||
| 5 | E, F, G, H (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 4 | Chemie (BOG) | |||
| 6 | I (A) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 7 | J, L (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 8 | K (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 9 | M, N (A, B) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
B: 340 - 350 (UniProt: P04695)
| PDB | External Database | Details |
|---|---|---|
| Leu 341 | Lys 341 | engineered mutation |
| Val 347 | Cys 347 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40292.9 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1091.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1677.1 | |
| All* | Total formula weight | 43061.0 |
