4J4L
Modular evolution and design of the protein binding interface
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Internalin B,REPEAT MODULES,Variable lymphocyte receptor B | polymer | 267 | 30059.1 | 2 | UniProt (A4L9V2) UniProt (Q4G1L3) Pfam (PF12354) Pfam (PF13855) Pfam (PF11921) In PDB | Listeria monocytogenes | |
2 | C, D | Interleukin-6 | polymer | 168 | 19196.9 | 2 | UniProt (P05231) Pfam (PF00489) In PDB | Homo sapiens (Human) | IL-6,B-cell stimulatory factor 2,BSF-2,CTL differentiation factor,CDF,Hybridoma growth factor,Interferon beta-2,IFN-beta-2 |
3 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A, B: 43 - 100 (UniProt: A4L9V2)
A, B: 101 - 209 (PDB: 4J4L)
A, B: 210 - 301 (UniProt: Q4G1L3)
C, D: 19 - 184 (UniProt: P05231)
PDB | External Database | Details |
---|---|---|
Ala 59 | Asp 59 | conflict |
A, B: 210 - 301 (UniProt: Q4G1L3)
PDB | External Database | Details |
---|---|---|
Leu 302 | - | expression tag |
Glu 303 | - | expression tag |
His 304 | - | expression tag |
His 305 | - | expression tag |
His 306 | - | expression tag |
His 307 | - | expression tag |
His 308 | - | expression tag |
His 309 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 17 | - | expression tag |
Ser 18 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 98512.1 | |
All* | Total formula weight | 98512.1 |