4J45
Crystal structure of XIAP-BIR2 domain with ATAA bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | E3 ubiquitin-protein ligase XIAP | polymer | 86 | 9936.1 | 2 | UniProt (P98170) Pfam (PF00653) In PDB | Homo sapiens (human) | Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked IAP |
| 2 | B | PEPTIDE (ALA-THR-ALA-ALA) | polymer | 4 | 332.4 | 1 | HOMO SAPIENS | ||
| 3 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, C: 152 - 236 (UniProt: P98170)
| PDB | External Database | Details |
|---|---|---|
| Gly 151 | - | expression tag |
| Ala 202 | Cys 202 | engineered mutation |
| Gly 213 | Cys 213 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 20204.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 20335.4 |
