4J1Y

The X-ray crystal structure of human complement protease C1s zymogen

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Complement C1s subcomponent	polymer	397	43766.5	2	UniProt (P09871) Pfam (PF00084) Pfam (PF00089)	Homo sapiens (human)	C1 esterase, Complement component 1 subcomponent s, Complement C1s subcomponent heavy chain, Complement C1s subcomponent light chain
2	C, D (A, B)	water	water		18.0	41	Chemie (HOH)

Sequence modifications

A, B: 292 - 688 (UniProt: P09871)

PDB	External Database	Details
Ala 436	Gln 436	engineered mutation
Ala 438	Ile 438	engineered mutation

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.