4J1Y
The X-ray crystal structure of human complement protease C1s zymogen
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Complement C1s subcomponent | polymer | 397 | 43766.5 | 2 | UniProt (P09871) Pfam (PF00084) Pfam (PF00089) In PDB | Homo sapiens (human) | C1 esterase, Complement component 1 subcomponent s, Complement C1s subcomponent heavy chain, Complement C1s subcomponent light chain |
| 2 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A, B: 292 - 688 (UniProt: P09871)
| PDB | External Database | Details |
|---|---|---|
| Ala 436 | Gln 436 | engineered mutation |
| Ala 438 | Ile 438 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 87532.9 | |
| All* | Total formula weight | 87532.9 |
