4J1T

Crystal structure of Thermus thermophilus transhydrogenase heterotrimeric complex of the Alpha1 subunit dimer with the NADP binding domain (domain III) of the Beta subunit in P2(1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, D, E (A, B, D, E)	NAD/NADP transhydrogenase alpha subunit 1	polymer	381	40851.3	4	UniProt (Q72GR8) Pfam (PF05222) Pfam (PF01262)	Thermus thermophilus
2	C, F (C, F)	NAD(P) transhydrogenase subunit beta	polymer	185	20018.2	2	UniProt (Q72GS0) Pfam (PF02233)	Thermus thermophilus	Nicotinamide nucleotide transhydrogenase subunit beta
3	G, J, K, L (A, D)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
4	H, M (B, E)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
5	I, N (C, F)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
6	O, P, Q, R, S... (A, B, C, D, E...)	water	water		18.0	232	Chemie (HOH)

Sequence modifications

A, B, D, E: 1 - 375 (UniProt: Q72GR8)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	203441.7
Non-Polymers*	Number of molecules	8
	Total formula weight	3182.0
All*	Total formula weight	206623.7

*Water molecules are not included.