4J1P
X-ray crystal structure of bromodomain 2 of human brd2 in complex with rvx208 to 1.08 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain containing 2, isoform CRA_a | polymer | 114 | 13375.4 | 1 | UniProt (Q658Y7) Pfam (PF00439) UniProt (by SIFTS) (P25440) In PDB | Homo sapiens (human) | Bromodomain-containing protein 2, Putative uncharacterized protein DKFZp313H139 |
| 2 | A | 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxyquinazolin-4(3H)-one | non-polymer | 370.4 | 1 | Chemie (1K0) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 254 | Chemie (HOH) |
Sequence modifications
A: 344 - 455 (UniProt: Q658Y7)
| PDB | External Database | Details |
|---|---|---|
| Ser 342 | - | expression tag |
| Met 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13375.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 432.5 | |
| All* | Total formula weight | 13807.9 |
