4J12
monomeric Fc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | human Fc fragment | polymer | 210 | 23787.8 | 1 | UniProt (Q6PYX1) Pfam (PF07654) UniProt (by SIFTS) (P01857) In PDB | Homo sapiens (human) | |
| 2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1317.2 | 1 | In PDB GlyTouCan (G39213VZ) | |||
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 236 - 444 (UniProt: Q6PYX1)
| PDB | External Database | Details |
|---|---|---|
| Asn 235 | - | expression tag |
| Asn 364 | Ser 265 | engineered mutation |
| Asn 407 | Tyr 308 | engineered mutation |
| Thr 409 | Lys 310 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23787.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1317.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 25326.2 |
