4J02
Crystal structure of hcv ns5b polymerase in complex with [(1R)-5,8-DICHLORO-1-PROPYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL]ACETIC ACID
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Genome polyprotein | polymer | 576 | 64285.6 | 2 | UniProt (O92972) Pfam (PF00998) In PDB | Hepatitis C virus isolate | Core protein p21, Capsid protein C, p21, Core protein p19, Envelope glycoprotein E1, gp32, gp35, Envelope glycoprotein E2, NS1, gp68, gp70, p7, Protease NS2-3, p23, Serine protease NS3, Hepacivirin, NS3P, p70, Non-structural protein 4A, NS4A, p8, Non-structural protein 4B, NS4B, p27, Non-structural protein 5A, NS5A, p56, RNA-directed RNA polymerase, NS5B, p68 |
2 | A, B | [(1R)-5,8-dichloro-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetic acid | non-polymer | 342.2 | 2 | Chemie (1JE) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
5 | water | water | 18.0 | 754 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 570 (UniProt: O92972)
PDB | External Database | Details |
---|---|---|
His 571 | - | EXPRESSION TAG |
His 572 | - | EXPRESSION TAG |
His 573 | - | EXPRESSION TAG |
His 574 | - | EXPRESSION TAG |
His 575 | - | EXPRESSION TAG |
His 576 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 128571.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 922.5 | |
All* | Total formula weight | 129493.8 |