4IXV
Crystal structure of human Arginase-2 complexed with inhibitor 2d: {(5R)-5-amino-5-carboxy-5-[1-(4-chlorobenzyl)piperidin-4-yl]pentyl}(trihydroxy)borate(1-)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Arginase-2, mitochondrial | polymer | 306 | 33231.7 | 3 | UniProt (P78540) Pfam (PF00491) In PDB | Homo sapiens | Kidney-type arginase, Non-hepatic arginase, Type II arginase |
2 | A, B, C | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
3 | A, B, C | BENZAMIDINE | non-polymer | 120.2 | 3 | Chemie (BEN) | |||
4 | A, B, C | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 3 | Chemie (BME) | |||
5 | A, B, C | {(5R)-5-amino-5-carboxy-5-[1-(4-chlorobenzyl)piperidin-4-yl]pentyl}(trihydroxy)borate(1-) | non-polymer | 399.7 | 3 | Chemie (XA1) | |||
6 | water | water | 18.0 | 633 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 99695.0 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 2123.6 | |
All* | Total formula weight | 101818.5 |