4IXH

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Cryptosporidium parvum

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Inosine-5'-monophosphate dehydrogenase	polymer	361	38506.4	4	UniProt (Q8T6T2) Pfam (PF00478) In PDB	Cryptosporidium parvum	IMP dehydrogenase, IMPD, IMPDH
2	A, B, C, D	INOSINIC ACID	non-polymer		348.2	4	Chemie (IMP)
3	A, C	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
4	A, B, C	(2S)-2-(naphthalen-1-yloxy)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]propanamide	non-polymer		409.4	4	Chemie (Q21)
5		water	water		18.0	486	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 89 (UniProt: Q8T6T2)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

A, B, C, D: 135 - 400 (UniProt: Q8T6T2)

PDB	External Database	Details
Ser 90	-	linker
Gly 91	-	linker
Gly 92	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	154025.7
Non-Polymers*	Number of molecules	13
	Total formula weight	3340.9
All*	Total formula weight	157366.6

*Water molecules are not included.