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4ITP

Structure of human carbonic anhydrase II bound to a benzene sulfonamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer25728932.61UniProt (P00918)
Pfam (PF00194)
Homo sapiens (human)Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II
2B, D, G, H, I
(A)
GLYCEROLnon-polymer92.15Chemie (GOL)
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4E
(A)
2-phenyl-N-(4-sulfamoylbenzyl)acetamidenon-polymer304.41Chemie (1GD)
5F
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
6J
(A)
waterwater18.0218Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28932.6
Non-Polymers*Number of molecules8
Total formula weight908.4
All*Total formula weight29841.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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