4ISI
Structure of FACTOR VIIA in complex with the inhibitor (6S)-N-(4-CARBAMIMIDOYLBENZYL)-1-CHLORO-3-(CYCLOBUTYLAMINO)-8,8-DIETHYL-4-OXO-4,6,7,8-TETRAHYDROPYRROLO[1,2-A]PYRAZINE-6-CARBOXAMIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H | Factor VII heavy chain | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (human) | |
| 2 | L | Factor VII light chain | polymer | 55 | 6030.8 | 1 | UniProt (P08709) Pfam (PF14670) In PDB | Homo sapiens (human) | |
| 3 | H | (6S)-N-(4-carbamimidoylbenzyl)-1-chloro-3-(cyclobutylamino)-8,8-diethyl-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamide | non-polymer | 471.0 | 1 | Chemie (1GG) | |||
| 4 | H | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34134.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 511.1 | |
| All* | Total formula weight | 34645.2 |
