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4IS6

Crystal structure of HLA-DR4 bound to GP100 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HLA class II histocompatibility antigen, DR alpha chainpolymer18221155.91UniProt (P01903)
Pfam (PF00993)
Pfam (PF07654)
Homo sapiens (human)HLA-DR4A, MHC class II antigen DRA
2B
(B)
HLA class II histocompatibility antigen, DRB1-4 beta chainpolymer19222520.01UniProt (P13760)
Pfam (PF00969)
Pfam (PF07654)
UniProt (by SIFTS) (P01911)
Homo sapiens (human)HLA-DR4B, MHC class II antigen DRB1*4, DR-4, DR4
3C
(C)
Melanocyte protein PMELpolymer162107.31UniProt (P40967)Homo sapiensME20-M, ME20M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog
4D, E
(A, B)
waterwater18.011Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight45783.2
All*Total formula weight45783.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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