4IRR

Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thymidylate synthase	polymer	315	35855.9	2	UniProt (Q9Y052) Pfam (PF00303)	Caenorhabditis elegans (nematode)
2	C, F (A, B)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	2	Chemie (UMP)
3	D, E, G, H (A, B)	2,3-DIHYDROXY-1,4-DITHIOBUTANE	non-polymer		154.3	4	Chemie (DTT)
4	I, J (A, B)	water	water		18.0	339	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71711.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1233.4
All*	Total formula weight	72945.2

*Water molecules are not included.