4IRE
Crystal structure of GLIC with mutations at the loop C region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | Proton-gated ion channel | polymer | 317 | 36274.8 | 5 | UniProt (Q7NDN8) Pfam (PF02931) In PDB | Gloeobacter violaceus | GLIC, Ligand-gated ion channel, LGIC |
| 2 | A, E, C | tetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside | non-polymer | 538.7 | 6 | Chemie (LMD) | |||
| 3 | D, A, B, E, C | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 10 | Chemie (PC1) | |||
| 4 | D, A, E, B, C | OXALATE ION | non-polymer | 88.0 | 17 | Chemie (OXL) | |||
| 5 | C, D, A, B, E | ACETATE ION | non-polymer | 59.0 | 10 | Chemie (ACT) | |||
| 6 | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 317 (UniProt: Q7NDN8)
| PDB | External Database | Details |
|---|---|---|
| Asn 91 | Asp 133 | engineered mutation |
| Gln 177 | Glu 219 | engineered mutation |
| Asn 178 | Asp 220 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 181373.8 | |
| Non-Polymers* | Number of molecules | 43 |
| Total formula weight | 13220.2 | |
| All* | Total formula weight | 194594.1 |
