4IR4
Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone (GSK2834113A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain adjacent to zinc finger domain protein 2B | polymer | 117 | 13618.7 | 1 | UniProt (Q9UIF8) Pfam (PF00439) | Homo sapiens (human) | hWALp4 |
| 2 | B (A) | 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone | non-polymer | 321.4 | 1 | Chemie (IR4) | |||
| 3 | C, D, E, F, G... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | K (A) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
A: 1858 - 1972 (UniProt: Q9UIF8)
| PDB | External Database | Details |
|---|---|---|
| Ser 1856 | - | expression tag |
| Met 1857 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13618.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 817.9 | |
| All* | Total formula weight | 14436.6 |
