4IR3
Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-amino-1-(pyrimidin-2-yl)indolizin-3-yl]ethanone (GSK2833282A)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bromodomain adjacent to zinc finger domain protein 2B | polymer | 117 | 13618.7 | 1 | UniProt (Q9UIF8) Pfam (PF00439) In PDB | Homo sapiens (human) | hWALp4 |
2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
4 | A | 1-[7-amino-1-(pyrimidin-2-yl)indolizin-3-yl]ethanone | non-polymer | 252.3 | 1 | Chemie (1FK) | |||
5 | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 1858 - 1972 (UniProt: Q9UIF8)
PDB | External Database | Details |
---|---|---|
Ser 1856 | - | expression tag |
Met 1857 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13618.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 622.7 | |
All* | Total formula weight | 14241.3 |