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4IQY

Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
O-acetyl-ADP-ribose deacetylase MACROD2polymer24027070.22UniProt (A1Z1Q3)
Pfam (PF01661)
Homo sapiens (human)MACRO domain-containing protein 2
2C, E
(A, B)
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATEnon-polymer559.32Chemie (AR6)
3D, F
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4G, H
(A, B)
waterwater18.0531Chemie (HOH)
Sequence modifications
A, B: 7 - 243 (UniProt: A1Z1Q3)
PDBExternal DatabaseDetails
Gly 4-expression tag
His 5-expression tag
Met 6-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight54140.4
Non-Polymers*Number of molecules4
Total formula weight1167.2
All*Total formula weight55307.6
*Water molecules are not included.

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PDB entries from 2025-12-24

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