4IQU
Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA nucleotidylexotransferase | polymer | 400 | 45704.0 | 1 | UniProt (P09838) Pfam (PF14716) Pfam (PF10391) Pfam (PF01909) Pfam (PF14791) In PDB | Mus musculus (mouse) | Terminal addition enzyme, Terminal deoxynucleotidyltransferase, TDT, Terminal transferase |
2 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
3 | A | (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid | non-polymer | 329.3 | 1 | Chemie (1FQ) | |||
4 | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A: 132 - 482 (UniProt: P09838)
A: 483 - 510 (UniProt: P09838)
PDB | External Database | Details |
---|---|---|
His 130 | - | expression tag |
Met 131 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 511 | - | expression tag |
Gly 512 | - | expression tag |
Ser 513 | - | expression tag |
Ser 514 | - | expression tag |
His 515 | - | expression tag |
His 516 | - | expression tag |
His 517 | - | expression tag |
His 518 | - | expression tag |
His 519 | - | expression tag |
His 520 | - | expression tag |
Ser 521 | - | expression tag |
Ser 522 | - | expression tag |
Gly 523 | - | expression tag |
Leu 524 | - | expression tag |
Val 525 | - | expression tag |
Pro 526 | - | expression tag |
Arg 527 | - | expression tag |
Gly 528 | - | expression tag |
Ser 529 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 45704.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 352.3 | |
All* | Total formula weight | 46056.3 |