4IQ6
Gsk-3beta with inhibitor 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen synthase kinase-3 beta | polymer | 426 | 47342.8 | 2 | UniProt (P49841) Pfam (PF00069) | Homo sapiens (human) | GSK-3 beta, Serine/threonine-protein kinase GSK3B |
| 2 | C, D (A, B) | 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine | non-polymer | 326.8 | 2 | Chemie (IQ6) |
Sequence modifications
A, B: 1 - 420 (UniProt: P49841)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Met -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 94685.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 653.6 | |
| All* | Total formula weight | 95339.3 |
