4IOU
Crystal structure of the HIV-1 Vif binding, catalytically active domain of APOBEC3F
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | DNA dC->dU-editing enzyme APOBEC-3F | polymer | 199 | 23211.9 | 4 | UniProt (Q8IUX4) Pfam (PF08210) In PDB | Homo sapiens (human) | Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F |
2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 185 - 373 (UniProt: Q8IUX4)
PDB | External Database | Details |
---|---|---|
Gly 175 | - | expression tag |
Pro 176 | - | expression tag |
Leu 177 | - | expression tag |
Gly 178 | - | expression tag |
Ser 179 | - | expression tag |
Pro 180 | - | expression tag |
Gly 181 | - | expression tag |
Ile 182 | - | expression tag |
Pro 183 | - | expression tag |
Gly 184 | - | expression tag |
Asp 196 | Tyr 196 | engineered mutation |
Gly 247 | His 247 | engineered mutation |
Arg 248 | Cys 248 | engineered mutation |
Ala 259 | Cys 259 | engineered mutation |
Lys 302 | Phe 302 | engineered mutation |
Asp 310 | Trp 310 | engineered mutation |
Ala 314 | Tyr 314 | engineered mutation |
Ala 315 | Gln 315 | engineered mutation |
Asp 355 | Lys 355 | engineered mutation |
Asp 358 | Lys 358 | engineered mutation |
Asp 363 | Phe 363 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 92847.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 261.6 | |
All* | Total formula weight | 93109.4 |