4IOU
Crystal structure of the HIV-1 Vif binding, catalytically active domain of APOBEC3F
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 1001 |
| Chain | Residue |
| A | HIS249 |
| A | CYS280 |
| A | CYS283 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 1001 |
| Chain | Residue |
| B | HIS249 |
| B | CYS280 |
| B | CYS283 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN C 1001 |
| Chain | Residue |
| C | HIS249 |
| C | CYS280 |
| C | CYS283 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1001 |
| Chain | Residue |
| D | HIS249 |
| D | CYS280 |
| D | CYS283 |
| D | HOH1108 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 39 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAErcFLswfaddilspntnyevtwytsws..........PCpe......CageV |
| Chain | Residue | Details |
| A | HIS249-VAL287 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"31792451","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6NIL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27139641","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31792451","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6NIL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | Cross-link: {"description":"(Microbial infection) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"23318957","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
