4IMP

The missing linker: a dimerization motif located within polyketide synthase modules

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Polyketide synthase extender modules 3-4	polymer	580	61599.6	4	UniProt (Q9ALM4) Pfam (PF18369) Pfam (PF08659)	Saccharopolyspora spinosa
2	E, F, G, H (A, B, C, D)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	4	Chemie (NDP)
3	I, J, K, L (A, B, C, D)	water	water		18.0	37	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 559 (UniProt: Q9ALM4)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	246398.3
Non-Polymers*	Number of molecules	4
	Total formula weight	2981.7
All*	Total formula weight	249380.0

*Water molecules are not included.