4IMJ
Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine-tune the Phosphatase Activity of Ssu72
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Symplekin | polymer | 339 | 37495.3 | 2 | UniProt (Q8MSU4) Pfam (PF11935) | Drosophila melanogaster (Fruit fly) | LD45768p |
| 2 | B, D (B, D) | CG14216 | polymer | 200 | 23130.3 | 2 | UniProt (Q9VWE4) Pfam (PF04722) | Drosophila melanogaster (Fruit fly) | LD40846p |
| 3 | E (F) | CTD | polymer | 19 | 2059.0 | 1 | Synthetic | ||
| 4 | F (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A, C: 19 - 351 (UniProt: Q8MSU4)
B, D: 1 - 195 (UniProt: Q9VWE4)
| PDB | External Database | Details |
|---|---|---|
| Gly 13 | - | EXPRESSION TAG |
| Pro 14 | - | EXPRESSION TAG |
| Gly 15 | - | EXPRESSION TAG |
| Ser 16 | - | EXPRESSION TAG |
| Gly 17 | - | EXPRESSION TAG |
| Met 18 | - | EXPRESSION TAG |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | EXPRESSION TAG |
| Pro -3 | - | EXPRESSION TAG |
| Gly -2 | - | EXPRESSION TAG |
| Ser -1 | - | EXPRESSION TAG |
| Gly 0 | - | EXPRESSION TAG |
| Asp 13 | Cys 13 | ENGINEERED MUTATION |
| Asn 144 | Asp 144 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 123310.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 95.0 | |
| All* | Total formula weight | 123405.1 |
