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4IMJ

Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine-tune the Phosphatase Activity of Ssu72

Functional Information from GO Data
ChainGOidnamespacecontents
B0004721molecular_functionphosphoprotein phosphatase activity
B0004722molecular_functionprotein serine/threonine phosphatase activity
B0005634cellular_componentnucleus
B0005847cellular_componentmRNA cleavage and polyadenylation specificity factor complex
B0006357biological_processregulation of transcription by RNA polymerase II
B0006369biological_processtermination of RNA polymerase II transcription
B0006397biological_processmRNA processing
B0008420molecular_functionRNA polymerase II CTD heptapeptide repeat phosphatase activity
B0016787molecular_functionhydrolase activity
B0016791molecular_functionphosphatase activity
B0031124biological_processmRNA 3'-end processing
D0004721molecular_functionphosphoprotein phosphatase activity
D0004722molecular_functionprotein serine/threonine phosphatase activity
D0005634cellular_componentnucleus
D0005847cellular_componentmRNA cleavage and polyadenylation specificity factor complex
D0006357biological_processregulation of transcription by RNA polymerase II
D0006369biological_processtermination of RNA polymerase II transcription
D0006397biological_processmRNA processing
D0008420molecular_functionRNA polymerase II CTD heptapeptide repeat phosphatase activity
D0016787molecular_functionhydrolase activity
D0016791molecular_functionphosphatase activity
D0031124biological_processmRNA 3'-end processing
F0003677molecular_functionDNA binding
F0006366biological_processtranscription by RNA polymerase II
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE PO4 B 201
ChainResidue
BASP13
BSER14
BSER15
BASN16
BMET17
BASN18
BARG19
BASN144

Functional Information from PROSITE/UniProt
site_idPS00115
Number of Residues7
DetailsRNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPS
ChainResidueDetails
FTYR-6-SER0
FTYR1-SER7

237735

PDB entries from 2025-06-18

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