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4ILW

Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-2 (TIMP-2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Metalloproteinase inhibitor 2polymer19421783.02UniProt (P16035)
Pfam (PF00965)
Homo sapiens (human)CSC-21K, Tissue inhibitor of metalloproteinases 2, TIMP-2
2C, D
(D, F)
Stromelysin-2polymer16518570.62UniProt (P09238)
Pfam (PF00413)
Homo sapiens (human)SL-2, Matrix metalloproteinase-10, MMP-10, Transin-2
3E, F, J, K
(D, F)
ZINC IONnon-polymer65.44Chemie (ZN)
4G, H, I, L, M...
(D, F)
CALCIUM IONnon-polymer40.16Chemie (CA)
5O, P, Q, R
(A, B, D, F)
waterwater18.0160Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight80707.2
Non-Polymers*Number of molecules10
Total formula weight502.1
All*Total formula weight81209.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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