4IL1

Crystal Structure of the Rat Calcineurin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Calmodulin, Calcineurin subunit B type 1, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	polymer	823	92698.8	4	UniProt (P62161) UniProt (P63100) UniProt (P63329) Pfam (PF13499) Pfam (PF00036) Pfam (PF00149) UniProt (by SIFTS) (P0DP29)	Rattus norvegicus (rat)	CaM, Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 3 regulatory subunit B alpha isoform 1, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform
2	E, F, G, H, I... (A, B, C, D)	CALCIUM ION	non-polymer		40.1	16	Chemie (CA)
3	U, V, W, X (A, B, C, D)	water	water		18.0	124	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 149 (UniProt: P62161)

PDB	External Database	Details
Gly 150	-	linker
Gly 151	-	linker
Gly 152	-	linker
Gly 153	-	linker
Gly 154	-	linker
Gly 155	-	linker
Gly 156	-	linker
Gly 157	-	linker
Gly 158	-	linker

A, B, C, D: 159 - 327 (UniProt: P63100)

PDB	External Database	Details
Gly 328	-	linker
Gly 329	-	linker
Gly 330	-	linker
Gly 331	-	linker
Gly 332	-	linker
Gly 333	-	linker

A, B, C, D: 334 - 815 (UniProt: P63329)

PDB	External Database	Details
Leu 816	-	expression tag
Glu 817	-	expression tag
His 818	-	expression tag
His 819	-	expression tag
His 820	-	expression tag
His 821	-	expression tag
His 822	-	expression tag
His 823	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	370795.2
Non-Polymers*	Number of molecules	16
	Total formula weight	641.2
All*	Total formula weight	371436.5

*Water molecules are not included.