4IJ0

Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA (5'-D(*CP*GP*CP*(C6G)P*AP*AP*TP*TP*CP*GP*CP*G)-3')	polymer	12	3721.4	2
2	C, D, E (A)	STRONTIUM ION	non-polymer		87.6	3	Chemie (SR)
3	F (B)	2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE	non-polymer		424.5	1	Chemie (HT)
4	G, H (A, B)	water	water		18.0	135	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	7442.9
Non-Polymers*	Number of molecules	4
	Total formula weight	687.4
All*	Total formula weight	8130.2

*Water molecules are not included.