4IIR
Crystal Structure of AMPPNP-bound Human PRPF4B kinase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase PRP4 homolog | polymer | 358 | 41933.5 | 2 | UniProt (Q13523) Pfam (PF00069) | Homo sapiens (human) | PRP4 kinase, PRP4 pre-mRNA-processing factor 4 homolog |
| 2 | C, F (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 3 | D, G, H, I (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 393 | Chemie (HOH) |
Sequence modifications
A, B: 657 - 1007 (UniProt: Q13523)
| PDB | External Database | Details |
|---|---|---|
| Met 656 | - | EXPRESSION TAG |
| His 1008 | - | EXPRESSION TAG |
| His 1009 | - | EXPRESSION TAG |
| His 1010 | - | EXPRESSION TAG |
| His 1011 | - | EXPRESSION TAG |
| His 1012 | - | EXPRESSION TAG |
| His 1013 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83866.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1420.9 | |
| All* | Total formula weight | 85287.9 |
