4IH7
Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RNA-directed RNA polymerase | polymer | 570 | 63354.7 | 2 | UniProt (P26663) Pfam (PF00998) | Hepatitis C virus (HCV) | NS5B, p68 |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | 3-(3-tert-butylphenyl)pyridin-2(1H)-one | non-polymer | 227.3 | 2 | Chemie (1ER) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 372 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 570 (UniProt: P26663)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 126709.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 585.4 | |
| All* | Total formula weight | 127294.9 |
