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4IGR

Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the agonist ZA302

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glutamate receptor, ionotropic kainate 3polymer25829092.51UniProt (P42264)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (rat)Glutamate receptor 7, GluR-7, GluR7
2B
(A)
(4R)-4-{3-[hydroxy(methyl)amino]-3-oxopropyl}-L-glutamic acidnon-polymer248.21Chemie (3ZA)
3C, D
(A)
POTASSIUM IONnon-polymer39.12Chemie (K)
4E
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5F
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
6G
(A)
waterwater18.051Chemie (HOH)
Sequence modifications
A: 432 - 546 (UniProt: P42264)
PDBExternal DatabaseDetails
Gly 429-expression tag
Pro 430-expression tag
Gly 431-expression tag
A: 669 - 806 (UniProt: P42264)
PDBExternal DatabaseDetails
Gly 547-linker
Thr 548-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29092.5
Non-Polymers*Number of molecules5
Total formula weight456.9
All*Total formula weight29549.3
*Water molecules are not included.

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PDB entries from 2025-11-19

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