4IG9
Structure of NAD-dependent protein deacetylase sirtuin-1 (open state, 2.64 A)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | NAD-dependent protein deacetylase sirtuin-1 | polymer | 281 | 31833.1 | 4 | UniProt (Q96EB6) Pfam (PF02146) In PDB | Homo sapiens (human) | hSIRT1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SirtT1 75 kDa fragment, 75SirT1 |
2 | B, D, F, H | NAD-dependent protein deacetylase sirtuin-1 | polymer | 31 | 3544.8 | 4 | UniProt (Q96EB6) In PDB | Homo sapiens (human) | |
3 | A, C, E, G | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
4 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 234 - 510 (UniProt: Q96EB6)
B, D, F, H: 641 - 665 (UniProt: Q96EB6)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
His -2 | - | expression tag |
Met -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Pro -5 | - | expression tag |
His -4 | - | expression tag |
Met -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 141511.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 261.6 | |
All* | Total formula weight | 141773.4 |