4ID7
ACK1 kinase in complex with the inhibitor cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Activated CDC42 kinase 1 | polymer | 273 | 31225.1 | 1 | UniProt (Q07912) Pfam (PF07714) | Homo sapiens (human) | ACK-1, Tyrosine kinase non-receptor protein 2 |
| 2 | B (A) | cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol | non-polymer | 372.4 | 1 | Chemie (1G0) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31225.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 468.5 | |
| All* | Total formula weight | 31693.6 |
