4I9I
Crystal structure of tankyrase 1 with compound 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tankyrase-1 | polymer | 217 | 25041.3 | 4 | UniProt (O95271) Pfam (PF00644) | Homo sapiens (human) | TANK1, ADP-ribosyltransferase diphtheria toxin-like 5, ARTD5, Poly [ADP-ribose] polymerase 5A, TNKS-1, TRF1-interacting ankyrin-related ADP-ribose polymerase, Tankyrase I |
| 2 | E, G, I, K (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, H, J, L (A, B, C, D) | N-(2-methoxyphenyl)-4-{[3-(4-oxo-3,4-dihydroquinazolin-2-yl)propanoyl]amino}benzamide | non-polymer | 442.5 | 4 | Chemie (1DY) PubChem (135566794) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1104 - 1314 (UniProt: O95271)
| PDB | External Database | Details |
|---|---|---|
| His 1315 | - | expression tag |
| His 1316 | - | expression tag |
| His 1317 | - | expression tag |
| His 1318 | - | expression tag |
| His 1319 | - | expression tag |
| His 1320 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 100165.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2031.5 | |
| All* | Total formula weight | 102196.8 |
