4I85
Crystal structure of transthyretin in complex with CHF5074 at neutral pH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 127 | 13777.4 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | ATTR, Prealbumin, TBPA |
| 2 | C, D (A, B) | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid | non-polymer | 325.2 | 2 | Chemie (H50) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27554.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 650.3 | |
| All* | Total formula weight | 28205.0 |
