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4I80

Crystal structure of human menin in complex with a high-affinity macrocyclic peptidomimetics

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMeninpolymer55061061.21UniProt (O00255)
Pfam (PF05053)
In PDB
Homo sapiens (Human)
2Bmacrocyclic peptidomimeticpolymer91127.41BIRD (PRD_000967)synthetic
Sequence modifications
A: 2 - 459 (UniProt: O00255)
PDBExternal DatabaseDetails
Ser 1-expression tag
A: 520 - 610 (UniProt: O00255)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62188.6
All*Total formula weight62188.6
*Water molecules are not included.

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PDB entries from 2024-09-11

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