4I80
Crystal structure of human menin in complex with a high-affinity macrocyclic peptidomimetics
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Menin | polymer | 550 | 61061.2 | 1 | UniProt (O00255) Pfam (PF05053) | Homo sapiens (Human) | |
| 2 | B (B) | macrocyclic peptidomimetic | polymer | 9 | 1127.4 | 1 | BIRD (PRD_000967) | synthetic |
Sequence modifications
A: 2 - 459 (UniProt: O00255)
A: 520 - 610 (UniProt: O00255)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62188.6 | |
| All* | Total formula weight | 62188.6 |






