4I7H

Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	peroxide stress sensing regulator	polymer	163	18899.4	2	UniProt (Q7CFI1) UniProt (by SIFTS) (A0A0H2UT39)	Streptococcus pyogenes	perR
2	C, F (A, B)	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI) PubChem (934)
3	D, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	G, H (A, B)	water	water		18.0	152	Chemie (HOH)

Sequence modifications

A, B: 1 - 155 (UniProt: Q7CFI1)

PDB	External Database	Details
Leu 156	-	expression tag
Glu 157	-	expression tag
His 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37798.7
Non-Polymers*	Number of molecules	4
	Total formula weight	248.2
All*	Total formula weight	38046.9

*Water molecules are not included.