4I7C
Siah1 mutant bound to synthetic peptide (ACE)KLRPV(23P)MVRPWVR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | E3 ubiquitin-protein ligase SIAH1 | polymer | 196 | 21978.1 | 2 | UniProt (Q8IUQ4) Pfam (PF21361) Pfam (PF03145) In PDB | Homo sapiens (human) | Seven in absentia homolog 1, Siah-1, Siah-1a |
2 | B, D | Protein phyllopod | polymer | 14 | 1709.2 | 2 | UniProt (Q27934) In PDB BIRD (PRD_000942) | Drosophila melanogaster | |
3 | A, C | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
4 | A, C | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
5 | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, C: 90 - 282 (UniProt: Q8IUQ4)
B, D: 113 - 125 (UniProt: Q27934)
PDB | External Database | Details |
---|---|---|
Gly 87 | - | expression tag |
Ser 88 | - | expression tag |
His 89 | - | expression tag |
Cys 156 | Thr 156 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ace 112 | - | acetylation |
Trp 123 | Thr 123 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 47374.6 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 498.0 | |
All* | Total formula weight | 47872.6 |