4I7C
Siah1 mutant bound to synthetic peptide (ACE)KLRPV(23P)MVRPWVR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| A | 0007275 | biological_process | multicellular organism development |
| A | 0008270 | molecular_function | zinc ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| C | 0007275 | biological_process | multicellular organism development |
| C | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 601 |
| Chain | Residue |
| A | CYS128 |
| A | CYS135 |
| A | HIS147 |
| A | HIS152 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 602 |
| Chain | Residue |
| A | CYS98 |
| A | CYS105 |
| A | HIS117 |
| A | CYS121 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 603 |
| Chain | Residue |
| A | PRO131 |
| A | HIS152 |
| A | SER154 |
| A | ASP177 |
| B | TRP123 |
| A | CYS130 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 601 |
| Chain | Residue |
| C | CYS128 |
| C | CYS135 |
| C | HIS147 |
| C | HIS152 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 602 |
| Chain | Residue |
| C | CYS98 |
| C | CYS105 |
| C | HIS117 |
| C | CYS121 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD C 603 |
| Chain | Residue |
| C | PRO131 |
| C | HIS152 |
| C | SER154 |
| D | TRP123 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 120 |
| Details | Zinc finger: {"description":"SIAH-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00455","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28546513","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5WZZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16085652","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28546513","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2A25","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5WZZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
