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4I7B

Siah1 bound to synthetic peptide (ACE)KLRPV(ABA)MVRPTVR

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
E3 ubiquitin-protein ligase SIAH1polymer19621976.12UniProt (Q8IUQ4)
Pfam (PF21361)
Pfam (PF03145)
Homo sapiens (human)Seven in absentia homolog 1, Siah-1, Siah-1a
2B, D
(B, D)
Protein phyllopodpolymer141567.02UniProt (Q27934)
BIRD (PRD_000939)
Drosophila melanogaster
3E, F, G, H
(A, C)
ZINC IONnon-polymer65.44Chemie (ZN)
4I, J, K, L
(A, B, C, D)
waterwater18.014Chemie (HOH)
Sequence modifications
A, C: 90 - 282 (UniProt: Q8IUQ4)
PDBExternal DatabaseDetails
Gly 87-expression tag
Ser 88-expression tag
His 89-expression tag
B, D: 113 - 125 (UniProt: Q27934)
PDBExternal DatabaseDetails
Ace 112-acetylation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47086.2
Non-Polymers*Number of molecules4
Total formula weight261.6
All*Total formula weight47347.8
*Water molecules are not included.

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PDB entries from 2025-12-24

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