4I73
Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Inosine-adenosine-guanosine-nucleoside hydrolase | polymer | 330 | 36167.6 | 4 | UniProt (Q57ZL6) Pfam (PF01156) | Trypanosoma brucei brucei | |
| 2 | E, M, Q, Y (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | F, N, R, Z (A, B, C, D) | (2R,3R,4S)-2-(hydroxymethyl)-1-[(4-hydroxythieno[3,2-d]pyrimidin-7-yl)methyl]pyrrolidine-3,4-diol | non-polymer | 297.3 | 4 | Chemie (MBY) | |||
| 4 | AA, BA, CA, G, H... (D, A, B, C) | NICKEL (II) ION | non-polymer | 58.7 | 17 | Chemie (NI) | |||
| 5 | DA, EA, FA, GA (A, B, C, D) | water | water | 18.0 | 670 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 327 (UniProt: Q57ZL6)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 144670.3 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2347.4 | |
| All* | Total formula weight | 147017.7 |
