4I72
Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with Immucillin A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Inosine-adenosine-guanosine-nucleoside hydrolase | polymer | 330 | 36167.6 | 2 | UniProt (Q57ZL6) Pfam (PF01156) | Trypanosoma brucei brucei | |
| 2 | C, K (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | D, L (A, B) | 3,4-PYRROLIDINEDIOL,2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)-2S,3S,4R,5R | non-polymer | 265.3 | 2 | Chemie (UA2) | |||
| 4 | E, F, G, M, N... (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 7 | Chemie (NI) | |||
| 5 | H, I, J (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 3 | Chemie (TRS) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 445 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 327 (UniProt: Q57ZL6)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72335.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1388.0 | |
| All* | Total formula weight | 73723.1 |
